Journal of Ethnopharmacology and Toxicology, Volume 1, Issue 1 : 6-12. Doi : 10.37446/jet/ra/1.1.2023.6-12
Review Article

OPEN ACCESS | Published on : 31-Dec-2023

Pesticides as an ovarian toxicant: a short review

  • Ichrak Khaled
  • Laboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems (LBBEEO), University of Gafsa, Gafsa, Tunisia.
  • Issam Saidi
  • Laboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems (LBBEEO), University of Gafsa, Gafsa, Tunisia.


Pesticides are extensively used in controlling agricultural pests.  Pesticides-exposure of a variety of populations manifest an array of adverse effects and a large wide of studies have shown that pesticides are extremely toxic to female reproductive systems. It has been reported that these pollutants induce oxidative stress, apoptosis, endocrine disorders, and epigenetic alterations which are directly implicated in the declining fertility of females in non-target species. The literature and information present in this review highlighted the toxic effect of pesticides on the female reproductive system along with their possible mechanisms in ovarian tissue.


pesticides, female, oxidative stress, apoptosis, endocrine, epigenetic


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