Journal of Ethnopharmacology and Toxicology | Volume 4 Issue 1 | Pages: 1-9 | Doi : 10.37446/jet/ra/4.1.2026.1-9

Review Article

OPEN ACCESS | Published on : 03-Mar-2026

A review on therapeutic potential of Karanthai Chooranam in traditional Tamil siddha medicine

Bhavadharani S M
• PG Student, Department of Biochemistry, RVS College of Arts and Science, Coimbatore, Tamil Nadu, India.

Sivasankar Murugesh
• Research Scholar, PG and Research Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu, India.

Soundarraj M
• Assistant Professor in Tamil, School of Science & Humanities, Kalaingar Karunanidhi Institute of Technology, Coimbatore, Tamil Nadu, India.

Dinesh Kumar M
• PG Student, Department of Biochemistry, RVS College of Arts and Science, Coimbatore, Tamil Nadu, India.


• Santhoshkumar Muthu
• Assistant Professor, Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu, India.


• Shamina S
• Associate Professor and Head, Department of Biochemistry, RVS College of Arts and Science, Coimbatore, Tamil Nadu, India.

Abstract

Karanthai Chooranam is a classical polyherbal formulation widely used in the traditional Tamil Siddha system of medicine for the management of various chronic ailments. It comprises medicinal herbs such as Sphaeranthus indicus, Clerodendrum serratum, Zingiber officinale, Piper nigrum, Piper longum, Dolomiaea costus, Psoralea corylifolia, Acorus calamus, Celastrus paniculatus, Terminalia chebula, Terminalia bellirica, Plumbago zeylanica, Nigella sativa, and rock salt, each possessing significant pharmacological properties. This review summarizes the traditional Siddha uses, phytochemical constituents, and therapeutic potential of the formulation based on classical Siddha literature and published scientific studies. Available evidence suggests that Karanthai Chooranam exhibits antioxidant, anti-inflammatory, antimicrobial, hepatoprotective, neuroprotective, immunomodulatory, digestive, and bronchodilatory activities, supporting its traditional use in the management of respiratory, gastrointestinal, skin, inflammatory, and metabolic disorders. Although the medicinal properties of the individual ingredients have been extensively reported, further pharmacological and clinical studies are required to validate the safety, efficacy, and therapeutic potential of Karanthai Chooranam as a complete formulation.

Keywords

Karanthai Chooranam, Siddha medicine, polyherbal formulation, Sphaeranthus indicus, phytochemistry, pharmacological activities, traditional medicine

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